{"id":52452,"date":"2025-02-12T10:12:18","date_gmt":"2025-02-12T02:12:18","guid":{"rendered":"https:\/\/labs.bioresis.com\/?p=52452"},"modified":"2025-02-12T10:30:46","modified_gmt":"2025-02-12T02:30:46","slug":"clinical-verification","status":"publish","type":"post","link":"https:\/\/labs.bioresis.com\/zh\/clinical-verification\/","title":{"rendered":"\u4e34\u5e8a\u9a8c\u8bc1"},"content":{"rendered":"
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Study 1<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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The efficacy of Grifolan extracted from Maitake (Grifola Frondasa) and Maitake powder was tested on several cancer patients (stage 2-4) aged 22-57 years old. Tumoural regression and improvement of symptoms were observed in 58.3% of hepatic cancer patients, 68.8% of primary breast cancer patients, and 62.5% of lung cancer patients. When Maitake was administered alongside chemotherapy, there was a significant increase (1.2-1.4 times) in immunocompetent cell activity as compared to isolated chemotherapy.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Study 2<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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15 female breast cancer patients (advanced stage) were treated with a D-fraction of Beta Glucan extracted from Grifola Frondosa as well as tablets of the same mushroom alongside chemotherapeutic treatment. 66.7% of them exhibited a significant reduction in tumour size and vomiting. There was also improvement in plasmatic tests and an increase in appetite.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Study 3<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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56 advanced stage cancer patients (12 gastric, 19 hepatic, 11 colorectal, 8 lung, 6 nasopharyngeal cancer) were divided into 2 groups of treatment. Group Experimental (n=30) and Group Placebo (n=26). Group Experimental was treated with tablets of polysaccharides extracted from 6 different mushrooms \u2013 3 times daily, 4 tablets each time (6g\/day). Group Placebo was given Poliactin-A \u2013 3 times daily, 1 tablet each time (30mg\/day). Both treatments began 7 days before chemotherapy and radiotherapy. Results demonstrated that polysaccharides inhibit protein synthesis of cancer cells, alleviate toxic reactions caused by anti-cancer drugs, improve immunity and secretion of IgA, as well as stimulate macrophages and monocytes action.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Study 4<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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8 different cancer patients (stage 2-4) aged 43-74 years old consumed 100mg D-fraction of the polysaccharide extracted from Grifola Frondosa(Grifolan) orally, and on a daily basis for 34 months. Examination proved that the posterior activity of natural killer cells in all patients increased significantly (1.2-2.7 times) when treated with Grifolan. The authors concluded the importance of D-fraction as a Biological Response Modifier, as it helped stimulate the natural killer cells through the secretion of IL-12 by macrophages.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Study 5<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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In a randomised, placebo-controlled, double-blind clinical trial, 22 patients were divided into 2 groups: Group Agaricus Sylvaticus (Beta Glucan 1-3,1-6- based polysaccharides), n=11, supplemented orally, twice daily (4.08 mg\/kg\/dia) for 3 months and Group Placebo, n=11. The Agaricus Sylvaticus group experienced normalised bowel movements and only 9% experienced no alteration of bowel functions. This proved that Agaricus Sylvaticus helps improve gastrointestinal function and reducing the adverse effects of chemotherapy.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Study 6<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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33 patients with gastric carcinoma were treated with 2 mg Lentinen (Beta Glucan 1-3,1-6-based polysaccharides) for 6 months after gastrectomy (4 times daily, in 2 or 4 week-intervals). 70% of the patients experienced a 50% increase in IL-1 basal production by macrophages. The result was even more significant in patients who took the 4 weeks dosage compared to 2 weeks.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Study 7<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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A randomised double-blind placebo controlled trial was conducted with 82 gastric carcinoma patients for a period of 2 months. The control group underwent chemotherapy only, while the experimental group underwent chemotherapy supplemented by 3g\/daily of polysaccharides extracted from Coriolus Versicolor (Beta Glucan 1-3,1-6-based). A significant increase (p < 0.05) was observed in natural killer cell activity, as well as in IL-2 and CD4\/CD88 levels, as compared to the control group.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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The aforementioned studies are abstracted from a series of clinical studies from \u201c The immunomodulator role of Beta-D-glucans as co-adjuvant for cancer therapy\u201d Rev Bras Nutr Clin 2006 21(2)163-8)<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\u8fdb\u4e00\u6b65\u4e86\u89e3 Bioresis<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\tIt seems we can't find what you're looking for.\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Study 1 The efficacy of Grifolan extracted from Maitake (Grifola Frondasa) and Maitake powder was tested on several cancer patients<\/p>","protected":false},"author":5,"featured_media":52454,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[185],"tags":[],"class_list":["post-52452","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-verification"],"_links":{"self":[{"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/posts\/52452","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/comments?post=52452"}],"version-history":[{"count":19,"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/posts\/52452\/revisions"}],"predecessor-version":[{"id":52489,"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/posts\/52452\/revisions\/52489"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/media\/52454"}],"wp:attachment":[{"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/media?parent=52452"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/categories?post=52452"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labs.bioresis.com\/zh\/wp-json\/wp\/v2\/tags?post=52452"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}